Washington Black is an eleven-year-old field slave who knows no other life than the Barbados sugar plantation where he was born. When his master's eccentric brother chooses him to be his manservant, Wash is terrified of the cruelties he is certain await him. But Christopher Wilde, or "Titch," is a naturalist, explorer, scientist, inventor, and abolitionist.

In the late 1630s, lured by the promise of the New World, George Ashby, set sail from England to settle in Barbados. He fell into the life of a sugar plantation owner by mere chance, but by the time he harvested his first crop, a revolution was fully under way: the farming of sugar cane, and the swiftly increasing demands for sugar worldwide, would not only lift George Ashby from abject poverty and shape the lives of his descendants, but it would also bind together ambitious white entrepreneurs and enslaved black workers in a strangling embrace.